Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.Biochemically, the indoleamine molecule derives from the amino acid tryptophan, via the (rate-limiting) hydroxylation of the 5 position on the ring (forming the intermediate 5-hydroxytryptophan), and then decarboxylation to produce serotonin. Serotonin is primarily found in the enteric nervous system located in the gastrointestinal tract (GI tract). However, it is also produced in the central nervous system (CNS), specifically in the Raphe nuclei located in the brainstem, Merkel cells located in the skin and taste receptor cells in the tongue. Additionally, serotonin is stored in blood platelets and is released during agitation and vasoconstriction, where it then acts as an agonist to other platelets.Approximately 90% of the human body's total serotonin is located in the enterochromaffin cells in the GI tract, where it regulates intestinal movements. About 8% is found in platelets and 1%-2% in the CNS. The serotonin is secreted luminally and basolaterally, which leads to increased serotonin uptake by circulating platelets and activation after stimulation, which gives increased stimulation of myenteric neurons and gastrointestinal motility. The remainder is synthesized in serotonergic neurons of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep.
Related Searches

If you like serotonin, try these related items.

Similar Topics

Customers looking for serotonin also searched for:

Sponsored Links
Banner 1
5-HTP 200mg Capsules, Serotonin Support for Sleep & Stress, 5-Hydroxytryptophan
5-HTP 200mg Capsules, Serotonin Support for Sleep & Stress, 5-Hydroxytryptophan
Price:
19.92 USD
Ends:
Dec 24, 03:54 pm
5-HTP  200mg Large Bottle
5-HTP 200mg Large Bottle "180 Capsules" Weight Management Mood Serotonin FRESH
Price:
17.25 USD
Ends:
Dec 12, 08:34 pm
SerotoninHelp 120 Capsules Natural Serotonin Supplement, Happy Hormone, Mood up.
SerotoninHelp 120 Capsules Natural Serotonin Supplement, Happy Hormone, Mood up.
Price:
18.75 USD
Ends:
Dec 21, 04:48 am
Dopaboost - L-DOPA Mucuna Extract 99% 350mg - serotonin brain food - 1 Bottle
Dopaboost - L-DOPA Mucuna Extract 99% 350mg - serotonin brain food - 1 Bottle
Price:
16.93 USD
Ends:
Dec 04, 05:23 pm
Mood Boost Support for Stress & Anxiety Relief 1100mg Serotonin Production Pills
Mood Boost Support for Stress & Anxiety Relief 1100mg Serotonin Production Pills
Price:
29.92 USD
Ends:
Dec 25, 05:36 pm
Serotonin Dopamine Liquescence 4 fl- Fresh & Free Shipping
Serotonin Dopamine Liquescence 4 fl- Fresh & Free Shipping
Price:
20.95 USD
Ends:
Dec 02, 09:53 pm
Natural Stacks Serotonin Brain Food Brain Supplement 30 Day Supply 60CT
Natural Stacks Serotonin Brain Food Brain Supplement 30 Day Supply 60CT
Price:
26.99 USD
Ends:
Dec 05, 10:41 pm
Mood Booster Supplement- Supports Brain Dopamine and Serotonin Levels To Feel
Mood Booster Supplement- Supports Brain Dopamine and Serotonin Levels To Feel
Price:
25.40 USD
Ends:
Dec 16, 02:56 am
Natural Stacks Serotonin Brain Food 60 Vege Capsules Exp 11/22+
Natural Stacks Serotonin Brain Food 60 Vege Capsules Exp 11/22+
Price:
17.99 USD
Ends:
Dec 17, 04:38 am
Sero Stress Reliever Serotonin Booster Mood Enhancer Sleep Brain Focus Pills
Sero Stress Reliever Serotonin Booster Mood Enhancer Sleep Brain Focus Pills
Price:
14.50 USD
Ends:
Dec 05, 12:31 pm
Sero Stress Reliever Serotonin Booster Mood Enhancer Sleep Brain Focus Pills
Sero Stress Reliever Serotonin Booster Mood Enhancer Sleep Brain Focus Pills
Price:
14.79 USD
Ends:
Dec 17, 06:50 pm
50 PURE L-Tryptophan Powder Capsules 500mg - Relaxation, Serotonin BOOST & SLEEP
50 PURE L-Tryptophan Powder Capsules 500mg - Relaxation, Serotonin BOOST & SLEEP
Price:
6.99 USD
Ends:
Dec 27, 07:49 pm
100 Capsules 500mg L-tryptophan Free Form Amino Acid Serotonin Brain Support
100 Capsules 500mg L-tryptophan Free Form Amino Acid Serotonin Brain Support
Price:
11.90 USD
Ends:
Dec 16, 08:24 pm
☀️ 5-HTP  (5-Hydroxytryptophan) 528mg  Neurotransmitter  Improved Serotonin ☀️
☀️ 5-HTP (5-Hydroxytryptophan) 528mg Neurotransmitter Improved Serotonin ☀️
Price:
26.39 USD
Ends:
Dec 26, 02:33 am
Mood Support Supplement Serotonin Booster, Anti Stress Calming Mood & Anxiety
Mood Support Supplement Serotonin Booster, Anti Stress Calming Mood & Anxiety
Price:
16.00 USD
Ends:
Dec 03, 02:18 pm
Dopamine - L-DOPA MUCUNA EXTRACT 99% 350mg - serotonin supplements - 1 Bottle
Dopamine - L-DOPA MUCUNA EXTRACT 99% 350mg - serotonin supplements - 1 Bottle
Price:
16.93 USD
Ends:
Jan 01, 02:12 pm
Serotonin: A Novel
Serotonin: A Novel
Price:
13.93 USD
Ends:
Dec 24, 03:31 pm
5-HTP 5htp 200mg 1/2/3 GIANT Bottles up to 360 Capsules Weight Mood Serotonin
5-HTP 5htp 200mg 1/2/3 GIANT Bottles up to 360 Capsules Weight Mood Serotonin
Price:
14.97 USD
Ends:
Dec 03, 11:56 pm
Natural Stacks - SEROTONIN - BRAIN FOOD - Positive Mood - 60 Capsules
Natural Stacks - SEROTONIN - BRAIN FOOD - Positive Mood - 60 Capsules
Price:
14.99 USD
Ends:
Dec 17, 09:44 am
Irwin Naturals 5-HTP Extra Serotonin Double Potency Mood Relaxation(Lot Of 3)NEW
Irwin Naturals 5-HTP Extra Serotonin Double Potency Mood Relaxation(Lot Of 3)NEW
Price:
32.21 USD
Ends:
Dec 30, 10:05 pm
Banner 2